A Red Carpet For Iron Metabolism

200 billion red blood cells rbcs are produced every day requiring more than 2 1015 iron atoms every second to maintain adequate erythropoiesis.

A red carpet for iron metabolism.

Iron is one of the most important minerals in the human body. Iron metabolism in erythroid cells red blood cells rbcs are formed from lineage committed progenitors during erythropoiesis a highly regulated process. It is also one of the most abundant minerals on the planet. 1 molecular medicine partnership unit european molecular biology laboratory and university of heidelberg im neuenheimer feld 350 69120 heidelberg germany.

Controlling iron levels in the body is a critically important part of many aspects of human health and disease. Iron is essential for many of the body s metabolic functions but its main role is in the production of hemoglobin the protein within red blood cells that binds oxygen for delivery to the various organs 2. Human iron metabolism is the set of chemical reactions that maintain human homeostasis of iron at the systemic and cellular level. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.

A red carpet for iron metabolism. Department of pediatric oncology hematology and immunology im neuenheimer feld 153 69120 heidelberg germany. Muckenthaler mu 1 rivella s 2 hentze mw 3 galy b 4. Rolling out the red carpet.

Among other themes this collection highlights a selection of seminal reviews from cell about metabolic conditions such as insulin resistance and diabetes atherosclerosis and heart disease and cholesterol biology metabolic syndrome as well as obesity and metabolic regulation of the fat tissue. Iron is also important in the production of myoglobin which. 2017 muckenthaler et al. These impressive number.

Cell a red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 15 iron atoms every second to maintain adequate erythropoiesis. A red carpet for iron metabolism. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron. Iron is both necessary to the body and potentially toxic.

Iron metabolism in erythroid cells red blood cells rbcs are formed from lineage committed progenitors during erythropoiesis a highly regulated process. Rolling out the red carpet. Metabolism is the basis of any biological function from the cellular to the organismal level.